PE Anti- Mouse ARG1 Antibody (FN047)
Sizes: 20T, 100T
Catalogue Numbers: PE-30324-20, PE-30324-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse ARG1
Form: Liquid
Conjugation: PE
Conjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: FN047
Isotype: IgG2b, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: ARG1 (Arginase 1), is a marker for the M2 anti-inflammatory macrophage subset that hydrolyzes l-arginine into urea and ornithine, and plays an important role in wound healing, antiviral immune responses, and atherosclerosis. The inherited deficiency of this enzyme results in argininemia, which is an autosomal recessive disorder characterized by hyperammonemia. Recent studies show that intracellular pathogens induce the expression of ARG1 in mouse macrophages through the Toll-like receptor (TLR) pathway. The deletion of this enzyme in macrophages favors host survival. Other studies indicate that ARG1 also plays a role in T cell responses and selective antagonists of ARG1 might prove beneficial in fighting diseases in which T-cell responses are inappropriately suppressed.
Synonyms: ARG1|Arginase 1|liver Arginase|ARG 1|Arg-1
Uniprot ID: Q61176
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 383
Category: Flow cytometryometry Antibodies
Research Use Only