PE Anti-Mouse CD122/IL-2RB Antibody (5H4)
Sizes: 25μg, 100μg
Catalogue Numbers: PE-30213U-25, PE-30213U-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD122/IL-2RB
Form: Liquid
Conjugation: PE
Conjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: 5H4
Isotype: IgG2a, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 Antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Synonyms: IL-2R subunit beta| CD122| High affinity IL-2 receptor subunit beta| IL-2 receptor subunit beta| IL-2RB| Il2rb| Interleukin-2 receptor subunit beta| p70-75
Uniprot ID: P16297
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 16185
Category: Flow cytometryometry Antibodies
Research Use Only