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PE-Cy5 Anti-Mouse CD80 Antibody (16-10A1) - PC5-30024

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PE-Cy5 Anti-Mouse CD80 Antibody (16-10A1)

Sizes: 50T, 100T

Catalogue Numbers: PC5-30024-50, PC5-30024-100

Citations, Manuals and MSDS Available upon request.

Target: Mouse CD80

Form: Liquid

Conjugation: PE-Cy5

Conjugation Information: PE-Cy5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).

Host: Armenian Hamster

Clonality: Monoclonal

Clone ID: 16-10A1

Isotype: IgG

Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Synonyms: Activation B7-1 antigen|B7|Cd80|T-lymphocyte activation antigen CD80

Uniprot ID: Q00609

Reactivity: Mouse

Tested Application: FC

Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Gene ID: 12519

Category: Flow cytometryometry Antibodies

Research Use Only