PE-Cy7 Anti-Rat CD44H Antibody (OX-49)
Sizes: 25μg, 100μg
Catalogue Numbers: PC7-30087U-25, PC7-30087U-100
Citations, Manuals and MSDS Available upon request.
Target: Rat CD44H
Form: Liquid
Conjugation: PE-Cy7
Conjugation Information: PE-Cy7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Host: Mouse
Clonality: Monoclonal
Clone ID: OX-49
Isotype: IgG2a, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 Antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 Antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 Antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.
Synonyms: CD44sH-CAM| CD44H| Pgp-1
Uniprot ID: P26051
Reactivity: Rat
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 12505
Category: Flow cytometryometry Antibodies
Research Use Only