5T4 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11901-50, MB11901-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q13641
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IP,
All Applications: WB: 1/500-1/1000 IP: 1/20
Background: 5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 46 kDa; Observed MW: 78 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of 5T4 in mouse brain, rat brain lysates using 5T4 antibody., Western blot analysis of 5T4 in 293T, C2C12 lysates using 5T4 antibody.
Alternative Name: 5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen; Trophoblast glycoprotein
Immunogen: A synthetic peptide of human 5T4
Conjugate: Unconjugated
Modification: Unmodified