ABflo® 450 Mouse anti-Human CD11b Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27475-100, A27475-200, A27475-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 127kDa Immunogen: Synthetic peptide.
Species: Human
GeneID: 3684
SWISS: P11215
Alternate Names: CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6
Source: Mouse
Isotype: IgG1, κ
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Immunology Inflammation, CDs, Neuroscience, Cell Type Marker, Stem Cells, Hematopoietic Progenitors, Mesenchymal Stem Cells
NCBI Alias: ITGAM
Modifications: Unmodified
Conjugate: ABflo® 450. Ex:406nm. Em:445nm.
Clone Number Info: AMC10008
Research Use Only