ABflo® 450 Mouse anti-Human CD3 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A25189-100, A25189-200, A25189-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 23kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 916
SWISS: P07766
Alternate Names: T3E; TCRE; IMD18; CD3epsilon
Source: Mouse
Isotype: mouse IgG2a
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs, T Cell Receptor Signaling Pathway, Stem Cells, Hematopoietic Progenitors
NCBI Alias: CD3E
Modifications: Unmodified
Conjugate: ABflo® 450. Ex:406nm. Em:445nm.
Clone Number Info: AMC50002
Research Use Only