ABflo® 488 Mouse anti-Human CD11c Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27558-100, A27558-200, A27558-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 128kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3687
SWISS: P20702
Alternate Names: CD11C; SLEB6
Source: Mouse
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors
NCBI Alias: ITGAX
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: AMC0552
Research Use Only