ABflo® 488 Rabbit anti-Human CD304/Neuropilin-1 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A22579-100, A22579-200, A22579-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 68kDa/71kDa/103kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 8829
SWISS: O14786
Alternate Names: NP1; NRP; BDCA4; CD304; VEGF165R
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, CDs, Neuroscience, Stem Cells, Cardiovascular, Angiogenesis
NCBI Alias: NRP1 Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC55418
Research Use Only