ABflo® 488 Rabbit anti-Human IFN-alpha/beta R2 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A25112-100, A25112-200, A25112-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 58kDa/37kDa/27kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3455
SWISS: P48551
Alternate Names: IFN-R; IMD45; IFNABR; IFNARB; IFN-R-2; IFN-alpha-REC; IFNAR2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Epigenetics Nuclear Signaling, Cancer, Tumor immunology, Signal Transduction, Immunology Inflammation, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway
NCBI Alias: IFNAR2
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC63166
Research Use Only