ABflo® 488 Rabbit anti-Human MMP9 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A23732-100, A23732-200, A23732-500
Citations, Manuals and MSDS Available upon request.
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Category: Monoclonal Antibodies
Application: FC (intra)
Cross Reactivity: Human
Protein Weight: 78kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 4318
SWISS: P14780
Alternate Names: MMP9; CLG4B; GELB; MANDP2; MMP-9; matrix metallopeptidase 9
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Tumor biomarkers, Invasion and Metastasis, Signal Transduction, G protein signaling, G2/M DNA Damage Checkpoint, Cell Biology and Developmental Biology, Apoptosis, Cytoskeleton, Extracellular Matrix, MMPs, Ubiquitin, Cardiovascular, Angiogenesis
NCBI Alias: MMP9
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC60377
Research Use Only