ABflo® 488 Rabbit anti-Human T-bet/Tbx21 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24572-100, A24572-200, A24572-500
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Category: Monoclonal Antibodies
Application: FC (intra)
Cross Reactivity: Human
Protein Weight: 58kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 30009
SWISS: Q9UL17
Alternate Names: TBX21; T-PET; T-bet; TBET; TBLYM; T-box 21
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume
Research Areas: Epigenetics and Nuclear Signaling, Transcription Factors, Immunology and Inflammation, Stem Cells, Hematopoietic Progenitors
NCBI Alias: TBX21
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC61886
Research Use Only