ABflo® 488 Rabbit anti-Mouse CD107b Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A25930-100, A25930-200, A25930-500
Citations, Manuals and MSDS Available upon request.
Background: Enables protein domain specific binding activity. Involved in several processes, including autophagosome maturation; protein stabilization; and protein targeting to lysosome involved in chaperone-mediated autophagy. Acts upstream of or within muscle cell cellular homeostasis. Located in late endosome membrane; lysosomal membrane; and phagocytic vesicle membrane. Is integral component of autophagosome membrane. Is expressed in central nervous system; egg cylinder; lung; and retina. Used to study Danon disease. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Orthologous to human LAMP2 (lysosomal associated membrane protein 2).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 46kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 16784
SWISS: P17047
Alternate Names: Mac3; LGP-B; CD107b; Lamp-2; Lamp II; Lamp-2a; Lamp-2b; Lamp-2c
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Tags and Cell Markers Subcellular Markers Organelles LysosomeSignal Transduction Metabolism Energy MetabolismImmunology Secreted Molecules Other secreted moleculesCardiovascular Heart Autophagy AutophagosomeStem Cells Hematopoietic Progenitors Myeloid Myeloid ProgenitorStem Cells Hematopoietic Progenitors Myeloid Monocytic LineageMetabolism Pathways and Processes Metabolic signaling pathways Energy transfer pathways Energy MetabolismMetabolism Pathways and Processes Metabolism processes Autophagy and mitophagy AutophagosomeCancer Cell Death Autophagy AutophagosomeNeuroscience Processes
NCBI Alias: Lamp2
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC63617
Research Use Only