ABflo® 488 Rabbit anti-Mouse CD130/gp130 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24983-100, A24983-200, A24983-500
Citations, Manuals and MSDS Available upon request.
Background: Contributes to interleukin-11 binding activity and interleukin-11 receptor activity. Involved in interleukin-6-mediated signaling pathway; intestinal epithelial cell development; and positive regulation of Notch signaling pathway. Acts upstream of or within several processes, including glycogen metabolic process; positive regulation of astrocyte differentiation; and regulation of Notch signaling pathway. Located in dendrite; external side of plasma membrane; and neuronal cell body. Is expressed in several structures, including alimentary system; brain; early conceptus; immune system; and reproductive system. Used to study rheumatoid arthritis and stomach cancer. Human ortholog(s) of this gene implicated in arteriosclerosis; hyper IgE recurrent infection syndrome 4; and hyperandrogenism. Orthologous to human IL6ST (interleukin 6 cytokine family signal transducer).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 102kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 16195
SWISS: Q00560
Alternate Names: CD130; gp130; D13Ertd699e; 5133400A03Rik
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cell Biology, Apoptosis, Intracellular, Associated Proteins, Immunology, Cell Type Markers, CD, Cytokines
NCBI Alias: Il6st
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC64569
Research Use Only