ABflo® 488 Rabbit anti-Mouse CD40 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27175-100, A27175-200, A27175-500
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 32kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 21939
SWISS: P27512
Alternate Names: IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology Adaptive Immunity B Cells CDCardiovascular Atherosclerosis Vascular Inflammation Innate and adaptive immunityStem Cells Hematopoietic Progenitors Lymphoid B Lymphocytic LineageStem Cells Hematopoietic Progenitors Myeloid Dendritic Cell LineageNeuroscience Processes
NCBI Alias: Cd40
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC71300
Research Use Only