ABflo® 488 Rabbit anti-Mouse JAM-1/CD321 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A25209-100, A25209-200, A25209-500
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable PDZ domain binding activity; integrin binding activity; and protein homodimerization activity. Involved in intestinal absorption; regulation of cytokine production; and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 32kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 16456
SWISS: O88792
Alternate Names: JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; 9130004G24; JAM-A/CD321
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cardiovascula, Blood, Platelets, Signal Transduction, Cytoskeleton/ECM, Cell Adhesion, Tight Junctions, Cardiovascular, Atherosclerosis, Vascular, Inflammation, Leukocyte recruitment, Cell junction molecules
NCBI Alias: F11r
Modifications: Unmodified
Conjugate: ABflo® 488. Ex:491nm. Em:516nm.
Clone Number Info: ARC65186
Research Use Only