ABflo® 594 Rabbit anti-Human CD87/PLAUR Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24232-100, A24232-200, A24232-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 31kDa/32kDa/36kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 5329
SWISS: Q03405
Alternate Names: PLAUR; CD87; U-PAR; UPAR; URKR; plasminogen activator, urokinase receptor
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Tumor biomarkers, Invasion and Metastasis, Signal Transduction, Kinase, Cell Biology and Developmental Biology, Extracellular Matrix, Immunology and Inflammation, CD markers, Cardiovascular, Blood
NCBI Alias: PLAUR
Modifications: Unmodified
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC61417
Research Use Only