ABflo® 594 Rabbit anti-Human Cytokeratin 8 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A24331-100, A24331-200, A24331-500
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Category: Monoclonal Antibodies
Application: FC (intra)
Cross Reactivity: Human
Protein Weight: 53kDa/56kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3856
SWISS: P05787
Alternate Names: KRT8; CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; keratin 8
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology and Developmental Biology, Cell Adhesion, Cytoskeleton, Intermediate Filaments
NCBI Alias: KRT8
Modifications: Unmodified
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC58354
Research Use Only