ABflo® 594 Rabbit anti-Mouse CD45 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A23709-100, A23709-200, A23709-500
Citations, Manuals and MSDS Available upon request.
Background: Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).
Category: Monoclonal Antibodies
Application: IF/ICC, FC
Cross Reactivity: Mouse
Protein Weight: 130KDa/140KDa/144KDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 19264
SWISS: P06800
Alternate Names: loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: IF/ICC,1:50 - 1:200|FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology, Adaptive immunity, B cells, CD
NCBI Alias: PTPRC
Modifications: Unmodified
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC60962
Research Use Only