ABflo® 594 Rabbit anti-Mouse RANK/CD265 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27180-100, A27180-200, A27180-500
Citations, Manuals and MSDS Available upon request.
Background: Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including circadian temperature homeostasis; positive regulation of fever generation by positive regulation of prostaglandin secretion; and tumor necrosis factor-mediated signaling pathway. Acts upstream of or within several processes, including hematopoietic or lymphoid organ development; mammary gland alveolus development; and positive regulation of bone resorption. Located in cell surface. Is expressed in bladder and lymphatic system. Human ortholog(s) of this gene implicated in Paget's disease of bone; autosomal recessive osteopetrosis 7; bone development disease; familial expansile osteolysis; and osteoporosis. Orthologous to human TNFRSF11A (TNF receptor superfamily member 11a).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 67kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 21934
SWISS: O35305
Alternate Names: OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology Innate Immunity Cytokines TNF SuperfamilySignal Transduction Adapters TransmembraneSignal Transduction Growth Factors/Hormones TNFSignal Transduction Cytoskeleton / ECM Extracellular Matrix Structures BoneCardiovascular Atherosclerosis Vascular Inflammation Inflammatory mediatorsNeuroscience Development
NCBI Alias: Tnfrsf11a
Modifications: Unmodified
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC65571
Research Use Only