ABflo® 647 Rabbit anti-Human Tie-2/CD202b Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27390-100, A27390-200, A27390-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 126kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 7010
SWISS: Q02763
Alternate Names: TIE2; VMCM; GLC3E; TIE-2; VMCM1; CD202B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, CDs, Stem Cells, Cardiovascular, Angiogenesis
NCBI Alias: TEK
Modifications: Unmodified
Conjugate: ABflo® 647. Ex:648nm. Em:664nm.
Clone Number Info: ARC72879
Research Use Only