ABflo® 647 Rabbit anti-Human VEGFR2/CD309 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A23357-100, A23357-200, A23357-500
Citations, Manuals and MSDS Available upon request.
Background: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 152kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 3791
SWISS: P35968
Alternate Names: FLK1; CD309; VEGFR; VEGFR2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Protein phosphorylation, Cancer, Invasion and Metastasis, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors, Cardiovascular, Angiogenesis, Hypoxia
NCBI Alias: KDR
Modifications: Unmodified
Conjugate: ABflo® 647. Ex:648nm. Em:664nm.
Clone Number Info: ARC60202
Research Use Only