ABflo® 647 Rabbit anti-Mouse CD209b/DC-SIGNR1 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26548-100, A26548-200, A26548-500
Citations, Manuals and MSDS Available upon request.
Background: CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 16kDa/33kDa/36kDa/37kDa Immunogen: Recombinant protein (or fragment).
Species: Mouse
GeneID: 69165
SWISS: Q8CJ91
Alternate Names: OtB7; SIGNR1; mSIGNR1; DC-SIGNR1; 1810030I22Rik
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology Innate Immunity Macrophage / InflammImmunology Cell Type Markers CD Myeloid CellsTags and Cell Markers Cell Type Markers Other Cell Types
NCBI Alias: Cd209b
Modifications: Unmodified
Conjugate: ABflo® 647. Ex:648nm. Em:664nm.
Clone Number Info: ARC69315
Research Use Only