ANXA7 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A21109-20, A21109-100
Citations, Manuals and SDS Available upon request.
Background: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
Synonyms: SNX; ANX7; SYNEXIN; ANXA7
GeneID: 310
Swiss-Prot: P20073
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 53kDa
Observed Molecular Weight: 47kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANXA7 (NP_001147.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Neuroscience, Calcium Signaling
Recommended Dilutions: WB: 1:100 - 1:500 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Extra Cellular Exosome, Nucleus
Positive Samples: HepG2, U-251MG, Mouse lung, Mouse placenta, Rat lung
Keywords: 310, sc-1932, sc-55488, sc-11389, Annexin 7, annexin A7, Annexin VII, Annexin7, ANX7, ANXA7, SNX, SYNEXIN, annexin VII, annexin-7, P20073, Annexin A7, Annexin-7, Synexin, sc1932, sc 1932, sc55488, sc 55488, sc11389, sc 11389
Symbol: ANXA7
Category: Monoclonal Antibodies
Research Use Only