APC Rabbit anti-Human/Mouse PDGFRα/CD140a Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26603-100, A26603-200, A26603-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human, Mouse
Protein Weight: 123kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 5156
SWISS: P16234
Alternate Names: CD140A; PDGFR2; PDGFR-2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Protein phosphorylation, Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, CDs, Cardiovascular, Angiogenesis
NCBI Alias: PDGFRA
Modifications: Unmodified
Conjugate: APC. Ex:650nm. Em:660nm.
Clone Number Info: ARC56217
Research Use Only