APC Rat anti-Mouse CD49f Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A28013-100, A28013-200, A28013-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This protein has been shown to heterodimerize with beta 4 to bind laminin and to form the main component of hemidesmosomes, which mediate attachment of epithelia to basement membranes. In mouse, deficiency of this gene is associated with absence of hemidesmosomes, severe skin blistering, and early post-natal death. In humans mutations of this gene are associated with epidermolysis bullosa. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse,Human
Protein Weight: 122kDa Immunogen: Synthetic peptide.
Species: Mouse
GeneID: 16403
SWISS: Q61739
Alternate Names: Cd49f; VLA-6; 5033401O05Rik
Source: Rat
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC, ≤0.5 µg per million cells in 100 µl volume
Research Areas: Signal Transduction Cytoskeleton / ECM Basal LaminaSignal Transduction Cytoskeleton / ECM Cell Adhesion Integrins AlphaStem Cells Embryonic Stem Cells Surface MoleculesStem Cells Hematopoietic Progenitors Myeloid Monocytic LineageDevelopmental Biology Embryogenesis Embryonic stem cells IntracellularNeuroscience Processes
NCBI Alias: CD49f
Modifications: Unmodified
Conjugate: APC. Ex:650nm. Em:660nm.
Clone Number Info: ATC0036
Research Use Only