BTF3 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10637-50, MB10637-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P20290
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Background: When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 22 kDa; Observed MW: 22 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of BTF3 in C6, 3T3 lysates using BTF3 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using BTF3 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: NACB; BTF3a; BTF3b; BETA-NAC
Immunogen: Recombinant protein of human BTF3
Conjugate: Unconjugated
Modification: Unmodified