C9 Rabbit Monoclonal Antibody
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Sizes: 50µl, 100µl
Catalogue Numbers: BS40066-50, BS40066-100
Swiss-Prot: P02748
Host: Rabbit
C9 Rabbit Monoclonal Antibody-BS40066
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Reactivity: Human
Applications: WB, IHC, IP,
All Applications: WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Background: C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71kDa. Normal plasma concentration is 60mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 molecules. This is the basis of the hydrophilic, protein-walled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.
Purification and Purity: Affinity-chromatography
Specificity: C9 Antibody detects endogenous levels of total C9
Bioworld Molecular Weight: ~ 70 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of C9 Rabbit monoclonal antibody at 1:500 dilution
Lane 1: human blood, Immunohistochemical analysis of paraffin-embedded human kidney, using C9 Antibody.
Alternative Name: Complement component C9; Comple Complement component C9bment component C9a;
Immunogen: A synthesized peptide derived from human C9
Modification: Unmodified
Conjugate: Unconjugated