CAMK2A Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22611-20, A22611-100
Citations, Manuals and SDS Available upon request.
Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms: CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha; CAMK2A
GeneID: 815
Swiss-Prot: Q9UQM7
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 54kDa
Observed Molecular Weight: 50kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 201-300 of human CAMK2A(NP_741960.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Protein phosphorylation, Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Kinase, Serine threonine kinases, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Microtubules, Endocrine Metabolism, Carbohydrate metabolism, Immunology Inflammation, B Cell Receptor Signaling Pathway, Neuroscience, Calcium Signaling, Cardiovascular, Heart, Hypertrophy
Recommended Dilutions: WB: 1:500 - 1:1000 | IF/ICC: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cell Junction, PreSynaptic Cell Membrane, Synapse
Positive Samples: 293T, U-87MG, Mouse brain, Mouse skeletal muscle, Rat brain
Keywords: 815, sc-5390, sc-5391, sc-1540, sc-55508, sc-9035, sc-13082, CaM kinase II subunit alpha, CaMK II subunit alpha, CAMK2, CAMK2A, CAMK2B, CAMK2D, CAMK2G, CAMKA, CaMKII alpha, KIAA0968, calcium/calmodulin dependent protein kinase II alpha, calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II alpha subunit, CaM-kinase II alpha chain, CaMK-II alpha subunit, CaMKIINalpha, caM kinase II subunit alpha, caMK-II subunit alpha, calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha-B subunit, calcium/calmodulin-dependent protein kinase type II alpha chain, Q9UQM7, Calcium/Calmodulin Dependent Protein Kinase II Alpha, Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) II Alpha, Calcium/Calmodulin-Dependent Protein Kinase Type II Alpha Chain, Calcium/Calmodulin-Dependent Protein Kinase II Alpha-B Subunit, CaM Kinase II Subunit Alpha, CaM Kinase II Alpha Subunit, CaM-Kinase II Alpha Chain, CaMK-II Subunit Alpha, CaMK-II Alpha Subunit, Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Alpha, EC 2.7.11.17, MRD53, sc5390, sc 5390, sc5391, sc 5391, sc1540, sc 1540, sc55508, sc 55508, sc9035, sc 9035, sc13082, sc 13082
Symbol: CAMK2A
Category: Monoclonal Antibodies
Research Use Only