CaMKII Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A0198-20, A0198-100
Citations, Manuals and SDS Available upon request.
Background: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.
Synonyms: CAM2; CAMK2; CAMKB; MRD54; CaMKIIbeta; CaMKII
GeneID: 816
Swiss Prot: Q13554
Tested Applications: ELISA, WB, IHC-P
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 73kDa
Observed Molecular Weight: 50kDa/55kDa/60kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CaMKII (NP_741960.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Kinase, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Cell Cycle, Immunology Inflammation, B Cell Receptor Signaling Pathway, Neuroscience, Cell Type Marker, Calcium Signaling, Neuron marker
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SH-SY5Y, U-251MG, Mouse brain, Rat brain, C6
Cellular Location: Cytoplasm, Cytoplasmic Side, Peripheral Membrane Protein, Sarcoplasmic Reticulum Membrane, Centrosome, Cytoskeleton, Microtubule Organizing Center,
Keywords: CAMK2B, CAM2, CAMK2, CAMKB, calcium/calmodulin dependent protein kinase II beta, calcium/calmodulin-dependent protein kinase type II subunit beta|CaM kinase II beta subunit|CaM-kinase II beta chain|caMK-II subunit beta|proline rich calmodulin-dependent protein kinase, Q13554, CaMKII
Symbol: CAMK2B
Category: Monoclonal Antibodies
Research Use Only