CARS Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A0438-20, A0438-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.
Synonyms: CARS; MDBH; CYSRS; MCDDBH; MGC:11246
GeneID: 833
Swiss Prot: P49589
Tested Applications: ELISA, WB, IHC-P
Reactivity: Human, Rat
Calculated Molecular Weight: 85kDa
Observed Molecular Weight: 85kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 650-748 of human CARS (P49589).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:1000 - 1:5000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Endocrine Metabolism, Amino acid metabolism, Nucleotide metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, A549, MCF7, U-87MG, Rat pancreas
Cellular Location: Cytoplasm
Keywords: sc-79224, sc-79225, sc-133495, sc-292476, CARS, CARS1, CYSRS, MGC:11246, cysteinyl-tRNA synthetase, cysteine--tRNA ligase, cytoplasmic, cysteine tRNA ligase 1, cysteine translase, P49589, 833, sc79224, sc 79224, sc79225, sc 79225, sc133495, sc 133495, sc292476, sc 292476, Cysteine tRNA ligase, cysteinyl tRNA synthetase, Unconjugated
Symbol: CARS1
Category: Monoclonal Antibodies
Research Use Only