Catalase Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A11220-20, A11220-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Synonyms: CAT; catalase; Catalase
GeneID: 847
Swiss Prot: P04040
Tested Applications: ELISA, WB, IHC-P
Reactivity: Mouse, Rat
Calculated Molecular Weight: 60kDa
Observed Molecular Weight: 60kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Catalase (P04040).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Heart
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse lung, Mouse liver, Mouse kidney, Rat lung, Rat liver, Rat kidney
Cellular Location: Peroxisome,
Keywords: CAT, catalase, P04040, Catalase
Symbol: CAT
Category: Monoclonal Antibodies
Research Use Only