Catenin beta Monoclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-70230-60, E-AB-70230-120, E-AB-70230-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: Catenin beta
Target Synonym: Beta catenin; Beta-catenin; Cadherin associated protein; Catenin (cadherin associated protein); beta 1; 88kDa; Catenin beta 1; Catenin beta-1; CATNB; CHBCAT; CTNB1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289
Research Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC
Isotype: IgG
Clonality: Monoclonal
Clone No.: 4A3H3
UNIProt ID: P35222,Q02248,Q9WU82
Background: CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Concentration: 420 μg/mL
Immunogen: Recombinant protein corresponding to Mouse β-catenin
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000, IHC 1:100-1:500
Calculated MW: 92kDa
Observed MW: 92kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only