Caveolin-3 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4891-20, A4891-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Synonyms: LQT9; MPDT; RMD2; VIP21; LGMD1C; VIP-21; Caveolin-3
GeneID: 859
Swiss-Prot: P56539
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 17kDa
Observed Molecular Weight: 19kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-151 of human Caveolin-3 (P56539).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Signal Transduction, ErbB-HER Signaling Pathway, Endocrine Metabolism, Insulin Receptor Signaling Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: RD, Mouse heart, Rat skeletal muscle
Cellular Location: Cell Membrane, Golgi Apparatus Membrane, Membrane, Peripheral Membrane Protein, Caveola,
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.