CBX1/HP1 beta Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22708-20, A22708-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms: CBX; M31; MOD1; p25beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta; CBX1/HP1 beta
GeneID: 10951
Swiss-Prot: P83916
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IHC-P
Calculated Molecular Weight: 21kDa
Observed Molecular Weight: 25kDa
Immunogen: Recombinant protein of human CBX1/HP1 beta.
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors
Recommended Dilutions: WB: 1:2000 - 1:10000 | IHC-P: 1:100 - 1:500
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Nucleus
Positive Samples: A-431, 293F
Keywords: sc-10212, sc-20699, CBX, CBX1, Chromobox protein homolog 1, Heterochromatin protein p25, HP1 BETA, HP1Hs beta, HP1Hsbeta, M31, MOD1, Modifier 1 protein, p25beta, HP1-BETA, HP1Hs-beta, chromobox 1, chromobox protein homolog 1, HP1 beta homolog, chromobox homolog 1 (HP1 beta homolog Drosophila ), heterochromatin protein 1 homolog beta, heterochromatin protein 1-beta, heterochromatin protein p25 beta, modifier 1 protein, P83916, 10951, HP1BETA, sc10212, sc 10212, sc20699, sc 20699, CBX1/HP1 beta
Symbol: CBX1
Category: Monoclonal Antibodies
Research Use Only