CBX2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A3294-20, A3294-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Synonyms: M33; CDCA6; SRXY5; CBX2
GeneID: 84733
Swiss-Prot: Q14781
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 56kDa
Observed Molecular Weight: 56kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 433-532 of human CBX2 (Q14781).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, Chromatin Remodeling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HT-29, 293T, Mouse liver, Mouse testis, Mouse brain, Rat testis
Cellular Location: Nucleus
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.