CBX8 Monoclonal Antibody
Catalogue Numbers: MB67216-50, MB67216-100
Sizes: 50µl, 100µl
Product: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Swiss-Prot: Q9HC52
Host: Mouse
Reactivity: Human
Applications: WB, FC
All Applications: WB (1/500 - 1/1000), FC (1/10 - 1/50)
Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Purification and Purity: This antibody is purified through a protein G column.
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Recognizes endogenous levels of CBX8 protein.
Extra Notes: Western blot analysis of CBX8 expression in 293 (A), Hela (B), A549 (C) whole cell lysates.
Bioworld Molecular Weight: ~ 50 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: PC3; RC1; Chromobox protein homolog 8; Polycomb 3 homolog; Pc3; hPc3; Rectachrome 1
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CBX8. The exact sequence is proprietary.
Conjugate: Unconjugated
Modification: Unmodified