CD11c Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A28244PM-20, A28244PM-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4) . The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Category: Monoclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human
Protein Weight: 128 kDa
Observed Molecular Weight: 145 kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 3687
SWISS: P20702
Alternate Names: CD11C; SLEB6
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:5000 - 1:10000 IF/ICC, 1:200 - 1:400 IHC-P, 1:2000 - 1:8000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000) ，a sequential dilution method is strongly recommended to ensure measurement accuracy.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors.
NCBI Alias: ITGAX
Research Use Only