CD163 Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A26411PM-20, A26411PM-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Category: Monoclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 121kDa/125kDa
Observed Molecular Weight: 170kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human/Mouse
GeneID: 9332/93671
SWISS: Q86VB7/Q2VLH6
Alternate Names: M130; MM130; SCARI1; CD163v2; CD163v3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:9000 IF-P, 1:2000 - 1:8000 IHC-P, 1:20000 - 1:80000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway, Cardiovascular.
NCBI Alias: CD163
Research Use Only