CD74 Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A26945PM-20, A26945PM-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Category: Monoclonal Antibodies
Applications: WB, IF/ICC, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 24kDa/26kDa
Observed Molecular Weight: 35-40kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human/Mouse
GeneID: 972/16149
SWISS: P04233-2/P04441-2
Alternate Names: II; p33; CLIP; DHLAG; HLADG; Ia-GAMMA
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:5000 - 1:20000 IF/ICC, 1:200 - 1:800 IF-P, 1:200 - 1:800 IHC-P, 1:4000 - 1:16000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs.
NCBI Alias: CD74
Research Use Only