CD8 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA10945-50, RA10945-100
Citations, Manuals and MSDS Available upon request.
Condition: Purified antibody in PBS containing 0.03% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: CD8A; MAL; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD antigen CD8a
Background: CD8a molecule(CD8A) Homo sapiens The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Applications: FCM; ELISA
Species Cross-Reactivity: Human
GeneID (Human): 925
SWISS: P01732
Source: Mouse
Research Use Only