CD86 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA10589-50, RA10589-100
Citations, Manuals and MSDS Available upon request.
Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86
Background: CD86 molecule(CD86) Homo sapiens This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011],
Applications: WB; ELISA
Species Cross-Reactivity: Human
GeneID (Human): 942
SWISS: P42081
Source: Mouse
Research Use Only