CD8A Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A23305PM-20, A23305PM-100
Citations, Manuals and MSDS Available upon request.
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Monoclonal Antibodies
Applications: WB, IF-P, IHC-P, mIHC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 21kDa/25kDa/30kDa
Observed Molecular Weight: 40kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human/Mouse
GeneID: 925/12525
SWISS: P01732/P01731
Alternate Names: CD8A;CD8;Leu2;MAL;p32
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50-1:200 IHC-P, 1:200 - 1:2000 mIHC, 1:200 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology & Inflammation, CD markers, Stem Cells.
NCBI Alias: CD8A
Research Use Only