COX4I2 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA11011-50, RA11011-100
Citations, Manuals and MSDS Available upon request.
Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: Western Blot: 1/1000 - 1/2000. Flow cytometry: 1/100 - 1/200. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.
Alternative Names: COX4I2; COX4L2; Cytochrome c oxidase subunit 4 isoform 2; mitochondrial; Cytochrome c oxidase subunit IV isoform 2; COX IV-2
Background: cytochrome c oxidase subunit 4I2(COX4I2) Homo sapiens Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008],
Applications: WB; FCM; IF/ICC
Species Cross-Reactivity: Human
GeneID (Human): 84701
SWISS: Q96KJ9
Source: Mouse
Research Use Only