EMAP II Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10875-50, MB10875-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q12904
Host: Rabbit
Reactivity: Human, Rat
Applications: WB,
All Applications: WB: 1/500-1/1000
Background: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 34 kDa; Observed MW: 34 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of EMAP II/AIMP1 in HT-1080 lysates using EMAP II antibody., Western blot analysis of EMAP II in C6 lysates using EMAP II antibody.
Alternative Name: p43; HLD3; EMAP2; SCYE1; EMAPII; AIMP1
Immunogen: A synthetic peptide of human EMAP II
Conjugate: Unconjugated
Modification: Unmodified