FGF-2 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA11204-50, RA11204-100
Citations, Manuals and MSDS Available upon request.
Condition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Store at: -20°C/1 year
Recommended Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification Technology: Affinity purification
Alternative Names: FGF2, FGFB, Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2
Background: fibroblast growth factor 2 (FGF2) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008],
Applications: WB, IHC-p, IF (paraffin section), ELISA
Species Cross-Reactivity: Human
GeneID (Human): 2247
SWISS: P09038
Source: Mouse
Immunogen: Purified recombinant fragment of FGF-2 expressed in E. Coli.
Category: Monoclonal
Research Use Only