HP1-γ Mouse Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA11431-50, RA11431-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 1:1000 icc 1:200
Alternative Names: CBX 3;CBX3 ;CBX3_HUMAN;Chromobox homolog 3 (HP1 gamma homolog, Drosophila);Chromobox homolog 3;Chromobox protein homolog 3 ;GAMMA; HECH;Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma;Heterochromatin protein HP1 gamma;HP1 gamma;HP1 gamma homolog;HP1Hs gamma;Modifier 2 protein.
Background: chromobox 3(CBX3) Homo sapiens At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011],
Applications: WB; IF/ICC; IP; IHC
Species Cross-Reactivity: Mouse; Human; Monkey; Hamster; Rat
Molecular Weight: 22
GeneID (Human): 11335
Protein MW (KDa): 22
SWISS: Q13185
Source: Mouse
Research Use Only