Human Kappa Light Chain Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A24693-20, A24693-100
Citations, Manuals and SDS Available upon request.
Background: Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain.
Synonyms: Km; HCAK1; IGKCD; Human Kappa Light Chain
Swiss-Prot: P01834
Reactivity: Human
Calculated Molecular Weight: 12kDa
Observed Molecular Weight: 25kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human Kappa Light Chain(P01834).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200
Research Areas: Immunology, Immunoglobulins, Light Chain Kappa
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Raji, SH-SY5Y
Cellular Location: Cytoplasmic, Secreted
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.