[KD Validated] SOD1 Rabbit PolymAb® - A27899PM

[KD Validated] SOD1 Rabbit PolymAb®

Sizes: 20μL, 100μL

Catalogue Numbers: A27899PM-20, A27899PM-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Category: Monoclonal Antibodies

Applications: WB, IP, IF/ICC, IF-P, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 16kDa

Observed Molecular Weight: 20kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 6647

SWISS: P00441

Alternate Names: ALS; SOD; ALS1; IPOA; STAHP; hSod1; HEL-S-44; homodimer

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:5000 - 1:20000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells IF/ICC, 1:200 - 1:800 IF-P, 1:200 - 1:800 IHC-P, 1:10000 - 1:40000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases.

NCBI Alias: SOD1

Research Use Only