[KO Validated] Fatty Acid Synthase (FASN) Rabbit PolymAb® - A22462PM

[KO Validated] Fatty Acid Synthase (FASN) Rabbit PolymAb®

Sizes: 20μL, 100μL

Catalogue Numbers: A22462PM-20, A22462PM-100

Citations, Manuals and MSDS Available upon request.

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Category: Monoclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 273kDa

Observed Molecular Weight: 273kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 2194

SWISS: P49327

Alternate Names: FAS; OA-519; SDR27X1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:2000 - 1:10000 IF/ICC, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Tumor biomarkers, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, AMPK Signaling Pathway, Neuroscience, Cardiovascular, Lipids, Fatty Acids.

NCBI Alias: FASN

Research Use Only